Barbra Streisand’s Question to Melissa McCarthy: “Did You Take Ozempic?”


In a recent Instagram post by actress Melissa McCarthy, an unexpected comment from none other than Barbra Streisand sparked curiosity and speculation. Streisand, an iconic figure in the entertainment industry, queried McCarthy about a weight-loss drug, Ozempic. This interaction between the two stars has stirred conversations online, drawing attention not only to their relationship but also to the topic of weight loss and celebrity influence.

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The Instagram Exchange

Melissa McCarthy, 53, took to Instagram to share a moment from the Center Theatre Group’s CTG The Gala event in Los Angeles, where she was accompanied by director Adam Shankman. In the caption, McCarthy expressed her excitement, playfully noting her proximity to her dream of dancing on stage. Among the flood of comments, one stood out – a question from Barbra Streisand herself, asking McCarthy if she had used Ozempic. While the comment has since been removed, it was captured by the Comments By Celebs Instagram account, fueling speculation and intrigue.

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Past Collaborations

Barbra Streisand
Barbra Streisand

This isn’t the first time McCarthy and Streisand have crossed paths. In 2016, they collaborated on Streisand’s ‘Encore’ album, performing a duet of “Anything You Can Do.” McCarthy has spoken fondly of Streisand, describing her as “really funny” and recalling their initial meeting with humor. Despite feeling nervous initially, McCarthy was charmed by Streisand’s down-to-earth demeanor, recounting an amusing anecdote of finding Streisand casually snacking on lunch meat upon opening the door.

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Barbra Streisand Reactions and Responses

Barbra Streisand
Barbra Streisand

While representatives for both Streisand and McCarthy have remained tight-lipped about the comment exchange, McCarthy received words of praise and encouragement from other celebrities in the Instagram post’s comment section. Glenn Close, Octavia Spencer, Elizabeth Banks, and Mariska Hargitay were among those who showered McCarthy with compliments, reflecting the supportive camaraderie within the entertainment industry.


The interaction between Barbra Streisand and Melissa McCarthy on Instagram has captivated fans and followers, sparking discussions about celebrity friendships, weight loss, and the power of social media interactions. While the specifics of Streisand’s question remain a mystery, the exchange serves as a reminder of the human connections that transcend fame and status.


1. What is Ozempic?

Ozempic is a prescription medication used to treat type 2 diabetes and aid in weight loss.

2. Why did Streisand ask McCarthy about Ozempic?

The reason behind Streisand’s question remains unknown, as neither party has commented publicly on the exchange.

3. How did McCarthy react to Streisand’s question?

McCarthy has not publicly addressed Streisand’s question about Ozempic.

4. What was the significance of McCarthy and Streisand’s previous collaboration?

McCarthy and Streisand’s duet on the ‘Encore’ album showcased their musical talents and shared love for performance.

5. Are McCarthy and Streisand friends?

While they have collaborated professionally and Streisand’s comment suggests some level of familiarity, the extent of their friendship is not publicly known.

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